• Long-term pain is unlikely to have a single cause.
  • Changes in the way nerves send pain messages have an important role. These changes are called CENTRAL SENSITISATION. You can’t see these changes on normal scans and x-rays.
  • For a detailed explanation of central sensitisation click here

  • Some people think our genetics (what we inherit from our family) plays a part in how our nervous system – and pain response – works.
  • People tend to move less, and differently, when they have pain. This can lead to weakness, stiffness & altered posture which in turn can worsen pain.

This slideshow looks at the causes of persistent pain: